Curriculum vitae with track record

ROLE IN THE PROJECT – HEAD of Research group:

Bergen CellStress, Tissue Engineering and Simulation in Biomedicine – BeCSTESim in Biomedicine

Project manager              x          Project partner

PERSONAL INFORMATION

Family name, First name: Bjørkum, Alvhild Alette

Date of birth: 10.02.1962

Sex: woman

Nationality: Norwegian

Researcher unique identifier(s) (ORCID, ResearcherID, etc.): Bjorkum AA Google Scholar https://scholar.google.no/scholar?hl=no&as_sdt=0%2C5&q=bj%C3%B8rkum+alvhild&oq=

 URL for personal web site:  https://www.hvl.no/person/?user=3600064 and  https://www.uib.no/en/rg/sc

EDUCATION

1996 PhD: Disputation date: 26*.05.1996* Ph.D. (Dr. Sci.) Neurophysiology, Department of Physiology, Medical Faculty, University of Bergen, Norway

1986 Master: M.Sci. (Cand. scient.) Human and zoological physiology, Department of Physiology, Medical Faculty, University of Bergen, Norway

CURRENT AND PREVIOUS POSITIONS

2002-2021 Associate Professor, Department of Biomedical Laboratory Sciences and Chemical Engineering, Faculty of Engineering, Bergen University College, Norway AND from 2017 Faculty of Engineering and Science, Western Norway University of Applied Sciences, Bergen, Norway

2001      Research coordinator, Department of Health, Bergen University Research Foundation

1999-     Postdoctoral stipend from The Norwegian Research Council.

1998-     Visiting Associate Professor from March 1998. Invited by Professor and Chairman Clifford B. Saper, Department of Neurology, Harvard Medical School, Harvard University, Massachusetts, USA

1997- 10 months Associate Professor from June 1997 Department of Physiology, Medical Faculty, University of Bergen Bilateral collab. and agreement exchange from 2002 until today - > 50 studs. *

1995-1997   Research Fellow, Fulbright Foundation, Department of Psychiatry Harvard Medical School, Invited by Director and Chairman Professor Robert W. McCarley * see above

1990-1994:         Research fellow, Department of Physiology, Medical Faculty, University of Bergen

1989-1990:         Senior Executive Officer at the Norwegian Research Council for Science and Humanities, Council for Medical Research (NRC, CMR), Oslo, Norway

1988-1989:         Scientist/Researcher at The Norwegian Medicine Control Authority, Oslo, Norway

FELLOWSHIPS, AWARDS AND PRIZES (if applicable)

2013      Equality-award from Bergen University College, Norway, 2012   Prof. qualification stipend from, Faculty og Engineering, Bergen University College, 2009     Lecturing-Milieu Award for Student-active Research at the Biomedical Laboratory Science Program at Bergen University College, Norway

1998      3-year grant Research Council of Norway, Division of Medicine and Health, Norway

1998      Sleep Research Society Award for Sleep Workshop: Molecular and Cellular Foundations of Sleep Disorders, LA, CA.

1997      Sleep Research Society Award for Sleep Workshop; Molecular Biological Studies of Sleep, Program for Basic Sleep Research, LA, CA.

1995      Fulbright Fellowship - Research/Lecturing Award from U.S. - Norway Fulbright Foundation, for research at Department of Psychiatry, Harvard University

1995      US-Norway Foundation; Scandinavia Scholarship Award

1995      Research Council of Norway, Division of Medicine and Health

1995      Sleep Research Society's travel fellowship for the World Federation of Sleep Research Society's International Conference

1993      Sleep Research Society's travel fellowship for the World Federation of Sleep

1994      Research Society's International Conference on the Cellular Consequences of Sleep

1991      Nordic Academy for Advanced Study, Award for One month at Department of Pharmacology, Karolinska Institutet, Karolinska Sjukhuset, Stockholm invited by Professor Urban Ungerstedt

1992      European Sleep Research Society's Congress Grant

1988      The Royal Ministry of Administration and Consumer Affair, Norway

1985      European Training Program grant, European Science Foundation

MOBILITY (research stays abroad lasting more than three months) (if applicable)

1998-2000           Visiting Associate Professor from March 1998. Invited by Professor and Chairman Clifford B. Saper, Department of Neurology, Harvard Medical School, Harvard University, Massachusetts, USA

1995-1997           Research Fellow, Fulbright Foundation, Department of Psychiatry Harvard Medical School, Invited by Director and Chairman Professor Robert W. McCarley

 

SUPERVISION OF GRADUATE STUDENTS AND RESEARCH FELLOWS (if applicable)

2003-2005 Supervisor ”Appoint to the Doctoral Committee” for PhD-student Marta Helliesen at Union Institute and University, Cincinnati, Ohio, USA.

2013-2015 Supervisor for Master in Innovation and Entrepreneurship-student Beate Kluge, siv. Ing. And Head engineer at Haukeland University Hospital and University of Bergen, Norway, joint master between UiO and BUC/HiB. Master thesis: Implementering av ny teknologi i offentlige forsknings- og helsemiljø med impedansspektroskopi som eksempel.

2015-2016 Supervisor for Master Kristian Svinø Hestetun, Master’s thesis in Software Engineering at Department of Computing, Mathematics and Physics, Bergen University College and Department of Informatics, University of Bergen, Norway

2015-2016 Co-supervisor for Markus Lippert Karlsen, Master’s thesis in Software Engineering at Department of Computing, Mathematics and Physics, Bergen University College and Department of Informatics, University of Bergen, Norway

2018- PhD-co-supervisor for Haja Sherief Nazimutheen Musthafa ad Simulation and tissue engineering, University of Bergen and Western Norway University of Applied Sciences, Bergen, Norway

 

TEACHING ACTIVITIES (if applicable)

2002-2022           Supervising 2-3 bachelor-group projects pr. Year in Biomedical Analytical Scientist education as part of 15-20 credits (ECTS) EVERY spring, Lecturing 10 ECTS in Anatomy and Physiology every autumn, Faculty of Engineering, Biomedical Laboratory Sciences Program, Bergen University College, Norway AND from 2017 by a new name: Faculty of Engineering and Science, Western Norway University of Applied Sciences, Bergen, Norway. Also, lecturing Cell biology 10 ECTS partly and now fully every spring semester from 2021.

1999-2001           25 % teaching/lecturing and other mandate work, Department of Physiology, Medical Faculty, University of Bergen, Norway. 1997 50 % teaching and other mandate work, Department of Physiology, Medical Faculty, University of Bergen, Norway

1990-1994           25% teaching and other mandate work, Department of Physiology, Medical Faculty,

University of Bergen

1991-1993          Physiology, lab. course and lecturing, 5 credit course for science students, master level, 3 days each year

1990-1993          Physiology, lab. course and lecturing, medical and dentistry studs., 3 weeks each year

1991-1992          Part time lecturer (50%) University Hospital Nursing School; in physiology and anatomy. 60 hours lecturing per semester pr. class, total 120 hours (two classes)

 

ORGANISATION OF SCIENTIFIC MEETINGS (if applicable)

2008 Initiated, organized and chaired a symposium and talk at the 19th Congress of the European Sleep Research Society, Glasgow, UK,

1999 Initiated, organizing and Chairman of one Symposium, one Focus Group and one Workshop on World Federation of Sleep Research Societies (WFSRS) Third International Congress, Dresden, Germany

1997 Scientific and organizing Head of the international meeting; In vivo Microdialysis in The Central Nervous System in Animals and Humans, December 6-7, 1997 at the Department of Physiology, University of Bergen, Norway

 

INSTITUTIONAL RESPONSIBILITIES

2002-2022Head of R&D Cell stress group ad sleep deprivation, MRI- and hyperbaric cellular stress, 2018-2022 Head of Biomedical laboratory Sciences BIOMARG-research group,

 

PROJECT MANAGEMENT EXPERIENCE

2002-2022           Head/Project leader of three main projects: Proteomic changes in serum and saliva and or cells after cellar stress in sleep-deprivation project (humans), also a hyperbar-project (animal, human planned) and a MRI-project (human and cellular models). Main title first project: Protein markers for cell stress after shiftwork, a model for stress on the organism - a proteomic and systems biological study

 

COMMISSIONS OF TRUST

20015- 2017 Member of Scientific Advisory Board for Computer Science, Software Engineering, Sensor Networks and Engineering Computing at Western Norway University of Applied Sciences, Bergen, Norway

MEMBERSHIPS OF ACADEMIES / SCIENTIFIC SOCIETIES (if applicable)

1997-                   Reviewer for Sleep Research Online

2003                      Ad hoc reviewer in Psychopharmacology

2006                     Ad hoc reviewer in Brain Research Bulletin

2007-                    Reviewer for Bioingeniøren, Norwegian Biomedical Scientific Journal

2018                      Ad hoc reviewer for Journal of Proteomics

2021                      Ad hoc reviewer for Molecular Neurobiology

MAJOR SCIENTIFIC AND EDUCATIONAL COLLABORATIONS

2008 – present Professor Allan Pack and Assoc. prof. Nirinjini Naidoo, University of Pennsylvania School of medicine, Center for Sleep and Respiratory Neurobiology, Pennsylvania, USA,

2005 - present Director and Chairman Professor Robert W. McCarley and Professor and Chairman Clifford B. Saper, Dept. of Psychiatry and Dept. of Neurology respectively (cellular sleep mechanisms), Harvard Medical School, Harvard University, Massachusetts, USA and VA-administration Hospital and Beth Israel Hospital respectively.

2005 – present Prof. Gabor Juhasz, Laboratory of Proteomics, Department of Physiology and Neurobiology (neuroproteomics in animal models for altered sleep and neurological disorders), ELTE Eötvös Loránd University, Budapest, Hungary

 

Original scientific publications with referee (total 25) - 10 selected, SEE FULL LIST ALSO pop.vit.:

9Porkka-Heiskanen, T., Strecker, R.E., Thakkar, M., Bjørkum, A.A., Green, R. W.  and McCarley R.W. Adenosine; A Mediator of the Sleep-Inducing Effects of Prolonged Wakefulness, Science, 1997, 276, (5316), iss. of 23 May, pp. 1265-1268. Citations: 1199

12 Chou, T, Bjørkum, A.A., Lu, J., Scammell, T. and Saper, C.B.; Afferents to the ventrolateral preoptic nucleus.  J Neurosci. 2002 Feb 1;22(3):977-990. Citations: 287

13 Lu, J., Bjørkum, A.A., Xu, M., Gaus, S.E., Shiromani, P. and Saper, C.B.; Selective Activation of the Extended Ventrolateral Preoptic Nucleus during Rapid Eye Movement Sleep. , J Neurosci. 2002 Jun 1;22(11): 4568-4576. Citations: 304

14 B Bjorvatn, J Grønli, F Hamre, E Sørensen, E Fiske, AA Bjørkum, CM Portas, C.M, and R Ursin. Effects of sleep deprivation on extracellular serotonin in hippocampus and frontal cortex of the rat

Neuroscience 113 (2), 323-330. Citations: 66

10 Strecker, R.E., Thakkar, M.M., Porkka-Heiskanen, T., Dauphin, L.J., Bjørkum, A.A. and McCarley R.W. Behavioral state-related changes of extracellular serotonin consentration in the pedunculopontine tegmental nucleus: A microdialysis study in freely moving animals. Sleep Research Online 2(2): 21‑27, 1999. Citations: 46

18 Shea JL, Mochizuki T, Sagvaag V, Aspevik T, Bjorkum AA, Datta S. Rapid eye movement (REM) sleep homeostatic regulatory processes in the rat: changes in the sleep-wake stages and electroencephalographic power spectra. Brain Res. 2008 Jun 5;1213:48-56. Epub 2008 Apr 7. Citations: 53

19 Takács E, Nyilas R, Szepesi Z, Baracskay P, Karlsen B, Røsvold T, Bjørkum AA, Czurkó A, Kovács Z, Kékesi AK, Juhász G. Matrix metalloproteinase-9 activity increased by two different types of epileptic seizures that do not induce neuronal death: a possible role in homeostatic synaptic plasticity.

Neurochem Int. 2010 May-Jun;56(6-7):799-809. Citations: 60

21 Arthurs OJ, Bjørkum AA. Safety in pediatric imaging: an update. Acta Radiol. 2013 Nov;54(9):983-90. Citations: 6

22 Kristensen, T., Jacobsen, V. and Bjørkum A.A. Data Clustering with Visualization of Proteomics Data, 2014, Lambert Academic Publishing, ISBN 978-3-659-31829-0 (book). Citations: ?

23 Arvid Hope, Linda B. Stuhr, Tina Pavlin, Alvhild Alette Bjørkum, Marit Grønning. MRI of the central nervous system in rats following heliox saturation decompression. Undersea and Hyperbaric Medical Journal. 2015 Jan./Feb. 42(1):57-64. Citations: 1

24 Bjørkum AA, Oveland E, Stuhr L, Havnes MB, Berven F, Grønning M, Hope A. Fast hyperbaric decompression after heliox saturation altered the brain proteome in rats. PLoS  One. 2017 Oct 4;12(10):e0185765. doi: 10.1371/journal.pone.0185765. eCollection 2017.PMID:28977037 Free Article Citations: 1

25 Bjørkum A.A., Carrasco Duran, A., Frode, B. et al. Human blood serum proteome changes after 6 hours of sleep deprivation at nightSleep Science Practice 5, 14 (2021). https://doi.org/10.1186/s41606-021-00066-2

3.            Research monographs and any translations thereof

1Ursin, R., Bjorvatn, B., Sommerfelt, L., Neckelmann, D. and Bjørkum, A. A. Studies on sleep-waking effects of serotonin reuptake inhibitors and receptor subtype involvement. Journal of Sleep Research, 1992, 1, 157-162. Citations: 8

2McCarley RW, Strecker, RE, Porkka-Heiskanen, T, Thakkar, M, Bjørkum, AA, Portas, CM, Rainnie, DG and Green, RW. Modulation of cholinergic neurons by serotonin and adenosine in the control of REM and Non-REM sleep. In Hayaishi O and Inoué S, eds. Sleep and Sleep Disorders:From Molecule to Behavior. Tokyo: Academic Press/Harcourt Brace Japan, 1997, pp 63 79. Citations: ?

3 Bjørkum, A.A., Pallesen, S. Holsten, F, Bjorvatn, B. Skiftarbeid og ulykkerrelevans for offshoreindustrien, Tidsskr Nor Lægeforen, 2004; 124(21):2773-5, review. Citations: 5

4 Pallesen, S. Holsten, F,  Bjørkum,A.A. , Bjorvatn, B. Søvnvansker ved nattarbeid, et problem for offshoreindustrien? Tidsskr Nor Lægeforen , 2004; 124(21):2770-2, review. Citations: 6

7.            Major contributions to the early careers of excellent researchers (if applicable)

Prof. dr. med Bjørn Bjorvatn, prof. Dr. sci. Janne Grønli (supervision together with prof. Dr. med Reidun Ursin). Also 2 years of contribution and supervision in the groups of Dr. med. prof and Chairmen’s; Robert W. McCarley, Harvard Medical School, Dept. of Psychiatry, Laboratory of Neuroscience and Clifford B. Saper, Department of Neurology, Harvard Medical School, Harvard University, Massachusetts, USA

8.            Examples of leadership in industrial innovation or design

Co-leadership with prof/dosent emeritus Terje Kristensen of Pattern Solutions  https://www.patternsolutions.no/

Inventor of Bjørkum BrainTrain Center – sleep, circadian, learning and memory training

https://system.easypractice.net/book/alvhild-alette-bjrkum?fbclid=IwAR3XXScaZsJeeAcnTwnkPdJad3z2qdXMs0AcqylAF8lLtIgtEbDSOCb9r_I&cookie_fixed=1#choose-service